Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 4/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.60 |
| ▸ | HTR1D | P28221 | 5/20 | 0.60 |
| ▸ | HTR1B | P28222 | 4/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658874 | 0.81 | ADRA2A (0.71) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL6054563 | 0.78 | ADRA2A (0.63) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL11180812 | 0.78 | ADRA2A (0.76) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL1369069 | 0.78 | ADRA2C (0.61) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL11761437 | 0.75 | ADRA2C (0.71) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL10414088 | 0.75 | ADRA2A (0.71) | CFBADRA2CADRA2AADRA2BHTR1D | |
| Pi-Clonidine SCHEMBL563884 | 0.75 | ADRA2A (1.00) | CFBADRA2CADRA2AADRA2BHTR1D | |
| Apraclonidine SCHEMBL34128 | 0.75 | ADRA2A (1.00) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL6054523 | 0.75 | ADRA2A (0.63) | CFBADRA2CADRA2AADRA2BHTR1D | |
| SCHEMBL11176814 | 0.75 | ADRA2A (0.79) | CFBADRA2CADRA2AADRA2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020229526-A1 | IMPROVED LYOPHILIZED FORMULATIONS INVOLVING HYALURONIC ACID AND PLASMATIC PROTEINS, AND USES THEREOF | BONE THERAPEUTICS SA (BE) | 2020-11-19 | — | — | WO | disclosed |
| EP-2900247-A1 | FORMULATIONS INVOLVING SOLVENT/DETERGENT-TREATED PLASMA (S/D PLASMA) AND USES THEREOF | Bone Therapeutics S.A. (BE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2013076160-A1 | SUSTAINED RELEASE FORMULATIONS USEFUL IN THE TREATMENT OF DISEASES | Université Libre de Bruxelles (BE) | 2013-05-30 | — | — | WO | disclosed |