SCHEMBL149769

SCHEMBL149769

O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)cc1O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.62
POLA1 P09884 1/20 0.60
POLD1 P28340 1/20 0.60
TYMS P04818 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6462543 1.00 POLB (0.62) POLBPOLA1POLD1TYMS
SCHEMBL3265084 0.90 TYMS (0.71) TYMS
SCHEMBL3265080 0.90 TYMS (0.71) TYMS
SCHEMBL17117799 0.89 LMNA (0.64) POLBPOLA1POLD1TYMS
SCHEMBL20906829 0.89 TK1 (0.64) POLBPOLA1POLD1TYMS
SCHEMBL23295972 0.89 POLB (0.61) POLBPOLA1POLD1TYMS
SCHEMBL21682516 0.89 POLB (0.78) POLBPOLA1POLD1TYMS
Deoxythymidine_Triphosphate SCHEMBL21275938 0.89 POLB (0.78) POLBPOLA1POLD1TYMS
SCHEMBL2132784 0.89 LMNA (0.64) POLBPOLA1POLD1TYMS
SCHEMBL5846553 0.89 TYMS (0.62) POLBPOLA1POLD1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050095606-A1 Partially double-stranded nucleic acids, methods of making, and use thereof HOKE GLENN (US) 2005-05-05 US claimed
US-6855500-B2 For detecting single nucleotide polymorphisms (SNPs) in diploid organisms using modified nucleotides/residues SEQUENOM, INC. (US) 2005-02-15 US claimed
US-20030165880-A1 Fluorescence-based genotyping NUVELO, INC. 2003-09-04 US claimed
EP-1332208-A2 PARTIALLY DOUBLE-STRANDED NUCLEIC ACIDS, METHODS OF MAKING, AND USE THEREOF Gene Logic, Inc. (US) 2003-08-06 EP claimed
WO-2002103013-A2 PARTIALLY DOUBLE-STRANDED NUCLEIC ACIDS, METHODS OF MAKING, AND USE THEREOF GENE LOGIC, INC. (US) 2002-12-27 WO claimed
US-20020127575-A1 Partially double-stranded nucleic acids, methods of making, and use thereof HOKE GLENN (US) 2002-09-12 US claimed
US-12173365-B2 Sequencing using non-natural nucleotides ULTIMA GENOMICS, INC. (US) 2024-12-24 US disclosed
US-20230348969-A1 METHODS AND SYSTEMS FOR NUCLEIC ACID SEQUENCING ULTIMA GENOMICS, INC. 2023-11-02 US disclosed
US-11649493-B1 Methods and systems for nucleic acid sequencing ULTIMA GENOMICS, INC. (US) 2023-05-16 US disclosed
US-20230022124-A1 SEQUENCING USING NON-NATURAL NUCLEOTIDES ULTIMA GENOMICS, INC. 2023-01-26 US disclosed
US-11326207-B2 Sequencing using non-natural nucleotides ULTIMA GENOMICS, INC. (US) 2022-05-10 US disclosed
US-20200216889-A1 SEQUENCING USING NON-NATURAL NUCLEOTIDES ULTIMA GENOMICS, INC. 2020-07-09 US disclosed
US-10662485-B2 Bioagent detection oligonucleotides IBIS BIOSCIENCES, INC. (US) 2020-05-26 US disclosed
WO-2005098047-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF BACTERIA ISIS PHARMACEUTICALS, INC. (US) 2005-10-20 WO disclosed
WO-2005092059-A2 COMPOSITIONS FOR USE IN IDENTIFICATION OF VIRAL HEMORRHAGIC FEVER VIRUSES ISIS PHARMACEUTICALS, INC. (US) 2005-10-06 WO disclosed
WO-2005089128-A2 RAPID IDENTIFICATION OF MICROBIAL AGENTS ISIS PHARMACEUTICALS, INC. (US) 2005-09-29 WO disclosed
US-6855500-B2 For detecting single nucleotide polymorphisms (SNPs) in diploid organisms using modified nucleotides/residues SEQUENOM, INC. (US) 2005-02-15 US disclosed
US-20030165880-A1 Fluorescence-based genotyping NUVELO, INC. 2003-09-04 US disclosed
EP-1332208-A2 PARTIALLY DOUBLE-STRANDED NUCLEIC ACIDS, METHODS OF MAKING, AND USE THEREOF Gene Logic, Inc. (US) 2003-08-06 EP disclosed
WO-2002103013-A2 PARTIALLY DOUBLE-STRANDED NUCLEIC ACIDS, METHODS OF MAKING, AND USE THEREOF GENE LOGIC, INC. (US) 2002-12-27 WO disclosed