SCHEMBL3265080

SCHEMBL3265080

O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)cc1O

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMS P04818 5/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265084 1.00 TYMS (0.71) TYMS
SCHEMBL6462543 0.90 POLB (0.62) TYMS
SCHEMBL149769 0.90 POLB (0.62) TYMS
Thymidine Monophosphate SCHEMBL8366987 0.88 POLB (0.80) TYMS
5-Fluorodeoxyuridylate SCHEMBL21901970 0.88 LMNA (0.71) TYMS
Thymidine Monophosphate SCHEMBL16280929 0.88 POLB (0.80) TYMS
5-Fluorodeoxyuridylate SCHEMBL15189164 0.88 LMNA (0.71) TYMS
Thymidine Monophosphate SCHEMBL3984895 0.88 POLB (0.80) TYMS
5-Fluorodeoxyuridylate SCHEMBL973436 0.88 LMNA (0.71) TYMS
SCHEMBL335865 0.88 TYMS (0.74) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
WO-2010022454-A1 METHODS, PRIMERS AND KITS FOR GENOTYPING NEOSPORA SPECIES AND STRAINS UNIVERSITY OF TECHNOLOGY, SYDNEY (AU) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 TYMS 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.