SCHEMBL1497690

SCHEMBL1497690

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nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48
ENPEP Q07075 4/20 0.40
SLC7A5 Q01650 2/20 0.40
SLC1A3 P43003 3/20 0.35
SLC1A2 P43004 3/20 0.35
SLC1A1 P43005 2/20 0.35
CASR P41180 1/20 0.33
P2RY10 O00398 2/20 0.31
GPR174 Q9BXC1 2/20 0.31
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL4493263 0.93 PTGS1 (0.42) PTGS1SLC7A11ENPEPSLC7A5SLC1A3
SCHEMBL6389078 0.85 PTGS1 (0.46) PTGS1SLC7A11ENPEPSLC7A5SLC1A3
Cysteine SCHEMBL8071966 0.83 ALOX15 (0.49) PTGS1SLC7A11ENPEPSLC7A5SLC1A3
SCHEMBL1537267 0.83 SLC7A5 (0.41) PTGS1SLC7A11SLC7A5SLC1A3SLC1A2
SCHEMBL135879 0.83 SLC7A5 (0.41) PTGS1SLC7A11SLC7A5SLC1A3SLC1A2
SCHEMBL28554464 0.81 SLC7A5 (0.40) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL891923 0.81 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1CASR
Tyrosine SCHEMBL3789571 0.81 SLC7A5 (0.58) PTGS1SLC7A5
SCHEMBL1964052 0.80 SLC7A5 (0.39) SLC7A5SLC1A3SLC1A2SLC1A1CASR
Valine SCHEMBL4409191 0.79 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100029005-A1 Method of Quantifying Membrane Protein By Using Mass Spectrometer TOHOKU UNIVERSITY (JP) 2010-02-04 US claimed
EP-1953542-A1 METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER TOHOKU UNIVERSITY (JP) 2008-08-06 EP claimed
WO-2024076136-A1 FUSION PEPTIDE COMPLEX COMPRISING TRANSMEMBRANE DOMAIN AND USE THEREOF 주식회사 안단테에프엠 2024-04-11 WO disclosed
WO-2024049232-A1 ANTIBACTERIAL PEPTIDE CONSISTING OF TRANSMEMBRANE PEPTIDE DOMAIN AND BASIC OR POLAR AMINO ACIDS AT OPPOSITE ENDS THEREOF AND VARIANTS THEREOF 주식회사 안단테에프엠 2024-03-07 WO disclosed
EP-1953542-B9 METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER UNIV TOHOKU (JP) 2013-11-13 EP disclosed
EP-1953542-B1 METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER UNIV TOHOKU (JP) 2013-04-10 EP disclosed
US-7901942-B2 Method of quantifying membrane protein by mass spectrometry using peptide selection criteria TOHOKU UNIVERSITY (JP) 2011-03-08 US disclosed
US-7829321-B2 Method for the production of bacterial toxins BAXTER INTERNATIONAL INC. (US) 2010-11-09 US disclosed
US-7790185-B2 Method for the production of bacterial toxins BAXTER INTERNATIONAL INC. (US) 2010-09-07 US disclosed
US-20100029005-A1 Method of Quantifying Membrane Protein By Using Mass Spectrometer TOHOKU UNIVERSITY (JP) 2010-02-04 US disclosed
EP-1953542-A1 METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER TOHOKU UNIVERSITY (JP) 2008-08-06 EP disclosed
US-20050100553-A1 Method for the production of bacterial toxins BAXTER HEALTHCARE S.A. (CH) 2005-05-12 US disclosed
US-6686180-B2 GENERATING MICROORGANISMAL GENE EXPRESSION INHIBITORS; OBTAIN MICROORGANISM, CULTURE, EXPRESS MODULATORS OF GENE ACTIVITY IN CULTURE, RECOVER GENE EXPRESSION INHIBITORS BAXTER INTERNATIONAL INC. 2004-02-03 US disclosed
EP-1268531-A2 METHOD FOR THE PRODUCTION OF BACTERIAL TOXINS BAXTER INTERNATIONAL INC. (US) 2003-01-02 EP disclosed
US-20020165344-A1 Method for the production of bacterial toxins BAXTER HEALTHCARE S.A. (CH) 2002-11-07 US disclosed
US-20020061555-A1 Method for the production of bacterial toxins BAXTER HEALTHCARE S.A. (CH) 2002-05-23 US disclosed
WO-2001074862-A2 METHOD FOR THE PRODUCTION OF BACTERIAL TOXINS BAXTER INTERNATIONAL INC. (US) 2001-10-11 WO disclosed
WO-1994012205-A1 DYNORPHIN A SUPPRESSION OF NATURAL KILLER CELL ACTIVITY THE ROCKEFELLER UNIVERSITY (US) 1994-06-09 WO disclosed
EP-0056249-B1 SYNTHETIC ANTIGENIC COMPOSITION AND PROCESS FOR MAKING SAME New York Blood Center, Inc. (US) 1985-06-26 EP disclosed
EP-0056249-A2 Synthetic antigenic composition and process for making same New York Blood Center, Inc. (US) 1982-07-21 EP disclosed