SCHEMBL1964052

SCHEMBL1964052

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nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.39
SLC1A3 P43003 3/20 0.34
SLC1A2 P43004 3/20 0.34
SLC1A1 P43005 2/20 0.34
ALOX15 P16050 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
KMT2A Q03164 1/20 0.34
CASR P41180 1/20 0.33
GRIK1 P39086 5/20 0.33
GRIA2 P42262 2/20 0.33
GRIA4 P48058 2/20 0.33
GRIK3 Q13003 2/20 0.33
GRIK5 Q16478 2/20 0.33
GRIK2 Q13002 2/20 0.33
GRIA1 P42261 1/20 0.33
ECE1 P42892 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL7763894 0.97 SLC7A5 (0.41) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL28554464 0.87 SLC7A5 (0.40) SLC7A5SLC1A3SLC1A2SLC1A1KMT2A
Asparagine SCHEMBL6130108 0.86 ALOX15 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
SCHEMBL8695381 0.85 NOS3 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
Aspartic Acid SCHEMBL28548999 0.84 SLC7A5 (0.42) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL891923 0.84 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL2482058 0.83 ALOX15 (0.53) SLC7A5SLC1A3SLC1A2SLC1A1ALOX15
Valine SCHEMBL17582481 0.83 SLC7A5 (0.37) SLC7A5
Valine SCHEMBL17582472 0.83 SLC7A5 (0.37) SLC7A5
SCHEMBL1537267 0.81 SLC7A5 (0.41) SLC7A5SLC1A3SLC1A2SLC1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331622-A2 INTEGRIN BINDING PEPTIDES AND USES THEREOF Universiteit Twente (NL) 2024-03-06 EP disclosed
US-20240025965-A1 INTEGRIN BINDING PEPTIDES AND USES THEREOF PRAKASH JAI (NL) 2024-01-25 US disclosed
US-20230407357-A1 BIOMANUFACTURING OF OLIGOSACCHARIDES AND DERIVATIVES FROM SIMPLE SUGAR ZYMTRONIX CATALYTIC SYSTEMS, INC. (US) 2023-12-21 US disclosed
WO-2023225364-A1 BIOMANUFACTURING OF OLIGOSACCHARIDES AND DERIVATIVES FROM SIMPLE SUGARS ZYMTRONIX CATALYTIC SYSTEMS, INC. (US) 2023-11-23 WO disclosed
EP-3365353-B1 INTEGRIN BINDING PEPTIDES AND USES THEREOF UNIV TWENTE (NL) 2023-11-22 EP disclosed
US-20230357318-A1 SOLUTION PHASE SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC SALTS MIMETOGEN PHARMACEUTICALS, INC. (CA) 2023-11-09 US disclosed
US-11753441-B2 Solution phase synthesis of beta-turn peptidomimetic cyclic salts MIMETOGEN PHARMACEUTICALS, INC. (CA) 2023-09-12 US disclosed
US-11634470-B2 Integrin binding peptides and uses thereof Prakash, Jai (NL) 2023-04-25 US disclosed
US-20210300966-A1 SOLUTION PHASE SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC SALTS MIMETOGEN PHARMACEUTICALS, INC. (CA) 2021-09-30 US disclosed
US-11078234-B2 Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts MIMETOGEN PHARMACEUTICALS, INC (CA) 2021-08-03 US disclosed
US-20150093799-A1 HISTIDYL-TRNA SYNTHETASES FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES ATYR PHARMA, INC. 2015-04-02 US disclosed
CN-101558309-B A method of diagnosis and kit therefor MACFARLANE BURNET INST FOR MEDICAL RES & PUBLIC HEALTH LTD 2014-02-26 CN disclosed
WO-2013191926-A1 SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS MIMETOGEN PHARMACEUTICALS, INC. (CA) 2013-12-27 WO disclosed
US-20130345395-A1 SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS MIMETOGEN PHARMACEUTICALS, INC. (CA) 2013-12-26 US disclosed
WO-2012049453-A2 COMPOSITIONS FOR TOPICAL APPLICATIONS VECTUM PHARMA S.L. (ES) 2012-04-19 WO disclosed
WO-2011072264-A2 METHODS AND COMPOSITIONS FOR BIOMASS TREATMENT QTEROS, INC. (US) 2011-06-16 WO disclosed
CN-101558309-A A method of diagnosis and kit therefor MACFARLANE BURNET INST FOR MED (AU) 2009-10-14 CN disclosed
CN-101090714-A Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation ACTELION PHARMACEUTICALS LTD (US) 2007-12-19 CN disclosed
EP-1606309-A2 ANTIMICROBIAL AGENTS FROM STREPTOCOCCUS MITIS AND STREPTOCOCCUS ORALIS The University of Bristol (GB) 2005-12-21 EP disclosed
WO-2004072093-A2 ANTIMICROBIAL AGENTS FROM STREPTOCOCCUS MITIS AND STREPTOCOCCUS ORALIS THE UNIVERSITY OF BRISTOL (GB) 2004-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753441-B2 Solution phase synthesis of beta-turn peptidomimetic cyclic salts PNISR, CGAS, NGLY1 SLC7A5 2485/4885SLC1A3 3404/4885SLC1A2 3970/4885
US-20210300966-A1 SOLUTION PHASE SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC SALTS PNISR, CGAS, NGLY1 SLC7A5 2485/4885SLC1A3 3404/4885SLC1A2 3970/4885
US-20130345395-A1 SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS NGLY1, PTMS, CCNY SLC7A5 2802/4885SLC1A3 4141/4885SLC1A2 4157/4885
US-20230357318-A1 SOLUTION PHASE SYNTHESIS OF BETA-TURN PEPTIDOMIMETIC CYCLIC SALTS PNISR, CGAS, NGLY1 SLC7A5 2485/4885SLC1A3 3404/4885SLC1A2 3970/4885
US-11078234-B2 Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts PNISR, RPP30, CXCL10 SLC7A5 2316/4885SLC1A3 3862/4885SLC1A2 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.