Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977379 | 0.90 | DGAT2 (0.42) | ROCK2ROCK1PPARGPTGDR2TP53 | |
| SCHEMBL14977707 | 0.90 | PPARG (0.39) | ROCK2ROCK1PPARGPTGDR2MAPT | |
| SCHEMBL14977623 | 0.88 | PPARG (0.39) | ROCK2ROCK1PPARGPTGDR2TP53 | |
| SCHEMBL14977301 | 0.87 | CSNK1D (0.36) | ROCK2ROCK1PTGDR2TP53MAPT | |
| SCHEMBL14977718 | 0.87 | ROCK2 (0.35) | ROCK2ROCK1PTGDR2TP53MAPT | |
| SCHEMBL14977224 | 0.86 | KIT (0.39) | PPARGPTGDR2MAPTLMNAKIT | |
| SCHEMBL2466314 | 0.86 | ROCK2 (0.44) | ROCK2ROCK1PPARGNPC1DGAT2 | |
| SCHEMBL14977778 | 0.86 | ROCK2 (0.39) | ROCK2PTGDR2MAPTMEN1NPC1 | |
| SCHEMBL14977569 | 0.86 | MAPK14 (0.37) | PPARGMAPTDGAT2 | |
| SCHEMBL14986300 | 0.85 | HDAC6 (0.41) | HDAC6PTGDR2TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |