Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977718 | 0.93 | ROCK2 (0.35) | CSNK1DCSNK1EROCK2ROCK1NPC1 | |
| SCHEMBL14977339 | 0.87 | ROCK2 (0.43) | ROCK2ROCK1NPC1PTGDR2KIT | |
| SCHEMBL14977379 | 0.86 | DGAT2 (0.42) | ROCK2ROCK1NPC1PTGDR2KIT | |
| SCHEMBL14977469 | 0.83 | NPC1 (0.38) | CSNK1DCSNK1ENPC1RAB9ATP53 | |
| SCHEMBL14977623 | 0.82 | PPARG (0.39) | ROCK2ROCK1NPC1PTGDR2KIT | |
| SCHEMBL14977707 | 0.81 | PPARG (0.39) | ROCK2ROCK1NPC1PTGDR2KIT | |
| SCHEMBL14976510 | 0.81 | CSNK1D (0.33) | CSNK1DCSNK1ENPC1RAB9ACTSA | |
| SCHEMBL14977224 | 0.81 | KIT (0.39) | CSNK1DCSNK1ENPC1RAB9APTGDR2 | |
| SCHEMBL14977196 | 0.80 | KIT (0.39) | CSNK1DCSNK1EPTGDR2KITTACR3 | |
| SCHEMBL14976233 | 0.79 | KIT (0.38) | ROCK2ROCK1NPC1RAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |