Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | DHODH | Q02127 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977362 | 0.91 | KMT2A (0.56) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977664 | 0.90 | DHODH (0.54) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977788 | 0.87 | DHODH (0.69) | KMT2ADHODHMEN1 | |
| SCHEMBL14977504 | 0.86 | DHODH (0.68) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14985372 | 0.84 | KMT2A (0.57) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977611 | 0.84 | DHODH (0.64) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977197 | 0.84 | MEN1 (0.61) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977635 | 0.84 | KMT2A (0.59) | KMT2ADHODHMEN1 | |
| SCHEMBL14977705 | 0.83 | MEN1 (0.63) | KMT2ADHODHMEN1NPC1RAB9A | |
| SCHEMBL14977583 | 0.83 | RAB9A (0.68) | KMT2ADHODHMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |