Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | DHODH | Q02127 | 9/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977701 | 0.90 | MEN1 (0.59) | MEN1KMT2ADHODHHSP90AA1NPC1 | |
| SCHEMBL14977744 | 0.90 | NOD1 (0.63) | MEN1KMT2ADHODHNPC1RAB9A | |
| SCHEMBL14977805 | 0.89 | KMT2A (0.61) | MEN1KMT2ADHODHHSP90AA1NPC1 | |
| SCHEMBL14977611 | 0.87 | DHODH (0.64) | MEN1KMT2ADHODHNPC1RAB9A | |
| SCHEMBL14977745 | 0.87 | MEN1 (0.57) | MEN1KMT2ADHODHHSP90AA1NPC1 | |
| SCHEMBL14977399 | 0.87 | DHODH (0.72) | MEN1KMT2ADHODHNPC1RAB9A | |
| SCHEMBL14977788 | 0.85 | DHODH (0.69) | MEN1KMT2ADHODH | |
| SCHEMBL14977583 | 0.85 | RAB9A (0.68) | MEN1KMT2ADHODHNPC1RAB9A | |
| SCHEMBL14977533 | 0.84 | KMT2A (0.78) | MEN1KMT2ADHODHHSP90AA1NPC1 | |
| SCHEMBL14985332 | 0.83 | KMT2A (0.58) | MEN1KMT2ADHODHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |