SCHEMBL14977909

COC1OC(COS(=O)(=O)O)[C@@H](OC2OC(OC=O)[C@@H](O[C@H]3OC(COS(=O)(=O)O)[C@@H](OC)[C@H](OOO)C3C)[C@@H](O)C2O)[C@H](O)C1C

nearest known ligand 0.41

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	6/20	0.41

▸	FGF1	P05230	4/20	0.39

▸	SERPINC1	P01008	2/20	0.37

▸	FGF2	P09038	1/20	0.34

▸	HPSE	Q9Y251	2/20	0.33

▸	BDNF	P23560	3/20	0.31

▸	PTN	P21246	2/20	0.31

▸	MDK	P21741	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9999568	0.88	F10 (0.54)	F10FGF1SERPINC1HPSEBDNF
SCHEMBL18539806	0.79	FGF1 (0.50)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL12552015	0.78	SERPINC1 (0.40)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL15996538	0.77	F10 (0.43)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL15996528	0.77	F10 (0.43)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL15449487	0.77	F10 (0.55)	F10FGF1SERPINC1HPSEBDNF
SCHEMBL15996518	0.77	F10 (0.43)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL26264734	0.77	FGF1 (0.48)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL15930574	0.76	F10 (0.39)	F10FGF1SERPINC1FGF2HPSE
SCHEMBL12552013	0.75	SERPINC1 (0.39)	F10FGF1SERPINC1FGF2HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8450297-B2	Synthesis of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides; rapid synthesis; high product yield; controlling coagulation and treating thrombosis	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US)	2013-05-28	—	—	US	disclosed