Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA7 | P43166 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687914 | 0.83 | HSD17B1 (0.46) | ALDH1A1HPGDCYP3A4MAPK1CA12 | |
| SCHEMBL7263165 | 0.80 | CA12 (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1310573 | 0.80 | MAPT (0.51) | ALDH1A1HPGDMAPK1CA12CA9 | |
| SCHEMBL16520525 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP3A4MAPK1CA12 | |
| SCHEMBL10943538 | 0.78 | AKR1C3 (0.46) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL30844550 | 0.78 | F2R (0.47) | MAPK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL136961 | 0.78 | F2R (0.47) | MAPK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL22423309 | 0.78 | ERN1 (0.47) | ALDH1A1HPGDCA12CA1CA2 | |
| SCHEMBL177377 | 0.78 | CA12 (0.67) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL30121064 | 0.78 | CA12 (0.67) | CYP3A4CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685454-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114685454-A | Organic compound, mixture, composition and organic electronic device | 广州华睿光电材料有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-8450355-B2 | Compounds for the treatment of inflammatory diseases | MERCK SHARP & DOHME CORP. (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110288077-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | SCHERING CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288077-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | TNF, ADAMTS13, MMP11 | ALDH1A1 1368/4885HPGD 475/4885CYP3A4 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.