Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 3/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966410 | 0.95 | GPR119 (0.40) | GPR119KCNH2SMOPANK3 | |
| SCHEMBL14965995 | 0.84 | GPR119 (0.44) | GPR119KCNH2 | |
| SCHEMBL14966714 | 0.82 | GPR119 (0.35) | GPR119SMO | |
| SCHEMBL14969159 | 0.79 | SLC6A9 (0.42) | GPR119KCNH2 | |
| SCHEMBL14978022 | 0.78 | TP53 (0.38) | GPR119PER2 | |
| SCHEMBL2598437 | 0.77 | GPR119 (0.39) | GPR119SMO | |
| SCHEMBL14966412 | 0.75 | GPR119 (0.40) | GPR119KCNH2SMOPANK3 | |
| SCHEMBL14968828 | 0.75 | DPP4 (0.33) | GPR119KCNH2PER2 | |
| SCHEMBL12185777 | 0.75 | GPR119 (0.40) | GPR119KCNH2SMO | |
| SCHEMBL15022798 | 0.75 | GPR119 (0.40) | GPR119KCNH2SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-10-16 | — | — | US | disclosed |
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-10-16 | — | — | US | disclosed |
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-10-16 | — | — | US | disclosed |
| WO-2013074641-A1 | PIPERIDINYL- SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | GPR119, UTS2R, GPR139 | GPR119 1/4885KCNH2 1308/4885SMO 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.