Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | MGLL | Q99685 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847472 | 0.90 | MAPT (0.52) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL10314810 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1GAAHTTKMT2A | |
| SCHEMBL5330200 | 0.72 | MAPT (0.58) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL832001 | 0.69 | ALDH1A1 (0.71) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL10126435 | 0.67 | MAPT (0.57) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL8973769 | 0.66 | TXNRD1 (0.66) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL9050843 | 0.66 | MAPT (1.00) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL14001552 | 0.65 | TXNRD1 (0.60) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL11571002 | 0.65 | MAPT (0.60) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL9665036 | 0.65 | MAPT (0.60) | MAPTALDH1A1TXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8450505-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |