Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.62 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.62 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335152 | 0.84 | TXNRD1 (0.58) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL9050843 | 0.83 | MAPT (1.00) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL8285548 | 0.83 | CA2 (0.63) | ALDH1A1MAPTCA2SMN1; SMN2TSHR | |
| SCHEMBL11876450 | 0.83 | CA2 (0.68) | ALDH1A1MAPTCA2TSHRMAPK1 | |
| SCHEMBL12291532 | 0.83 | CA2 (0.63) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL3712418 | 0.83 | CA2 (0.56) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL499483 | 0.83 | GAA (0.56) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL8427051 | 0.81 | CA2 (0.62) | ALDH1A1MAPTCA2SMN1; SMN2TDP1 | |
| SCHEMBL8540296 | 0.81 | CA2 (0.60) | ALDH1A1MAPTCA2TXNRD1TXNRD3 | |
| SCHEMBL9051152 | 0.81 | MAPT (0.84) | ALDH1A1MAPTCA2TXNRD1TXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518736-A | Preparation method of 4-(beta-hydroxyethyl sulfone sulfate)-1,3-phenylenediamine and degreased product thereof | 浙江劲光实业股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-9079870-B2 | Thiol mediated/activated prodrugs of sulfur dioxide (SO2) having anti-bacterial activity | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH-PUNE (IN) | 2015-07-14 | — | — | US | disclosed |
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8779166-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8779166-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8779166-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH -PUNE (IN) | 2014-05-01 | — | — | US | disclosed |
| US-20130217853-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-22 | — | — | US | disclosed |
| US-20040261199-A1 | Fibre-reactive dyes their preparation and their use | HUNTSMAN INTERNATIONAL LLC | 2004-12-30 | — | — | US | disclosed |
| US-20040255404-A1 | Fibre-reactive azo dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC | 2004-12-23 | — | — | US | disclosed |
| EP-1470195-A1 | FIBRE-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | Ciba SC Holding AG (CH) | 2004-10-27 | — | — | EP | disclosed |
| EP-1458818-A1 | FIBRE-REACTIVE DYES, THEIR PREPARATION AND THEIR USE | Ciba SC Holding AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003040239-A1 | FIBRE-REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003033599-A1 | FIBRE-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-24 | — | — | WO | disclosed |
| EP-0603116-B1 | Reactive azo dyestuffs | CIBA SC HOLDING AG (CH) | 2000-05-10 | — | — | EP | disclosed |
| WO-1997043345-A1 | REACTIVE AZO DYES WITH A REACTIVE-ANCHOR-CARRYING DIAZO COMPONENT FROM THE SERIES OF M-PHENYLENE DIAMINE | ZAMPONI, ANDREA | 1997-11-20 | — | — | WO | disclosed |
| US-5424405-A | Colorfast yellow wool dyes | CIBA-GEIGY CORPORATION (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0603116-A1 | Reactive azo dyestuffs | CIBA-GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | TST, SQOR, MPST | ALDH1A1 918/4885MAPT 3745/4885CA2 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.