Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034687 | 0.91 | PRSS1 (0.41) | PRSS1PRSS2PRSS3HDAC8KMO | |
| SCHEMBL14141387 | 0.83 | PKM (0.38) | PRSS1PRSS2PRSS3HPGDKDM4E | |
| SCHEMBL14204477 | 0.79 | MAPT (0.42) | HPGDKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14654376 | 0.79 | PRSS1 (0.58) | PRSS1PRSS2PRSS3HDAC8KMO | |
| SCHEMBL21152339 | 0.76 | PRSS1 (0.58) | PRSS1PRSS2PRSS3HDAC8KMO | |
| SCHEMBL21745729 | 0.75 | PRSS1 (0.54) | PRSS1PRSS2PRSS3HPGDKDM4E | |
| SCHEMBL21151946 | 0.75 | ALOX5 (0.49) | MAPTGPR52DHODH | |
| SCHEMBL20391726 | 0.74 | PRSS1 (0.60) | PRSS1PRSS2PRSS3HDAC8KMO | |
| SCHEMBL17196527 | 0.73 | PRSS1 (0.58) | PRSS1PRSS2PRSS3HDAC8KMO | |
| SCHEMBL15290753 | 0.73 | HDAC8 (0.41) | PRSS1PRSS2PRSS3HDAC8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013073896-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2013-05-23 | — | — | WO | disclosed |