Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8254893 | 0.81 | NPC1 (0.67) | NPC1RAB9AMAPTNFKB1NFKB2 | |
| SCHEMBL8295389 | 0.81 | PRSS1 (0.62) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL21746252 | 0.80 | PRSS1 (0.48) | PRSS1PRSS2PRSS3RAB9AMAPT | |
| SCHEMBL14141387 | 0.76 | PKM (0.38) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL14979082 | 0.75 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAPTSMN1; SMN2 | |
| SCHEMBL26241053 | 0.75 | PRSS1 (0.62) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL18871269 | 0.74 | ALOX15 (0.43) | NPC1RAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28548430 | 0.73 | PRSS1 (0.61) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL26474021 | 0.73 | PRSS1 (0.61) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL24454583 | 0.73 | PRSS1 (0.65) | PRSS1PRSS2PRSS3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |