Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901987 | 1.00 | NR1H4 (0.50) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL3897985 | 0.90 | NR1H4 (0.62) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL31019193 | 0.90 | NR1H4 (0.62) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL30910306 | 0.90 | NR1H4 (0.48) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL1205128 | 0.90 | NR1H4 (0.48) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL8417822 | 0.87 | HDAC1 (0.53) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL7930745 | 0.87 | TSHR (0.46) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL30965061 | 0.87 | TSHR (0.46) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL474132 | 0.86 | ALDH1A1 (0.53) | NR1H4L3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL16415399 | 0.86 | HDAC1 (0.47) | NR1H4L3MBTL1HDAC1NAMPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |