Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965061 | 1.00 | TSHR (0.46) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL30964980 | 0.90 | NR1H4 (0.48) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL1205921 | 0.90 | TSHR (0.47) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL14979282 | 0.87 | NR1H4 (0.50) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL30901987 | 0.87 | NR1H4 (0.50) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL134817 | 0.86 | ALDH1A1 (0.61) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL27434364 | 0.86 | L3MBTL1 (0.44) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL14969490 | 0.86 | TSHR (0.57) | TSHRL3MBTL1NAMPTGAAATR | |
| SCHEMBL6629351 | 0.86 | ROCK2 (0.46) | TSHRL3MBTL1NAMPTGAAKDM4A | |
| SCHEMBL14965812 | 0.84 | PTGES (0.56) | TSHRGAAHPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |