Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750181 | 0.86 | GAA (0.42) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL26287884 | 0.83 | CYP4F2 (0.51) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL29974722 | 0.83 | CYP4F2 (0.51) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL4880397 | 0.81 | CA12 (0.38) | KMT2AMEN1 | |
| SCHEMBL25841901 | 0.79 | SORT1 (0.36) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL14023609 | 0.79 | SORT1 (0.45) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL30100715 | 0.79 | SORT1 (0.45) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL25841898 | 0.78 | NNMT (0.49) | MAPTNPSR1ALDH1A1HTTNNMT | |
| SCHEMBL7982235 | 0.75 | MTOR (0.44) | MAPTNPC1MAPK1NNMTPOLB | |
| SCHEMBL28065181 | 0.75 | MAPT (0.45) | KMT2AMEN1MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |