SCHEMBL14979302

SCHEMBL14979302

CCOc1ccc(CCc2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.53
NQO1 P15559 1/20 0.50
RELA Q04206 1/20 0.49
SIGMAR1 Q99720 1/20 0.48
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA7 P36544 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LTB4R Q15722 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44
BCHE P06276 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6306948 0.91 LTA4H (0.63) LTA4HNQO1RELANPC1RAB9A
SCHEMBL8944052 0.91 LTA4H (0.63) LTA4HNQO1RELANPC1RAB9A
SCHEMBL14174217 0.86 KCNH2 (0.50) NQO1SMN1; SMN2KMT2ALTB4RLTB4R2
SCHEMBL26319795 0.86 KCNH2 (0.50) NQO1SMN1; SMN2KMT2ALTB4RLTB4R2
SCHEMBL10884813 0.85 LTA4H (0.57) LTA4HNQO1RELACHRNB4CHRNA3
SCHEMBL8206442 0.84 LTA4H (0.55) LTA4HSIGMAR1NPC1RAB9AMEN1
SCHEMBL8943653 0.84 LTA4H (0.55) LTA4HNQO1RELAMAPTL3MBTL1
SCHEMBL7876585 0.84 LTA4H (0.55) LTA4HSIGMAR1NPC1RAB9AMEN1
SCHEMBL12012640 0.84 LTA4H (0.55) LTA4HNQO1RELAMAPTL3MBTL1
SCHEMBL24231223 0.82 ALDH1A1 (0.54) MAPTSMN1; SMN2MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450033-B2 Electrography; facsimiles, printers, copiers; polyurethanes RICOH COMPANY, LTD. (JP) 2013-05-28 US disclosed