SCHEMBL14979358

SCHEMBL14979358

c1ccc(-c2cccc(-c3cccc(-c4cnc(-n5c6ccccc6c6ccc7ccccc7c65)nc4)c3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPK10 P53779 1/20 0.34
MET P08581 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
FGFR1 P11362 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
PDE10A Q9Y233 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979314 0.99 FGFR1 (0.35) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979401 0.95 NPC1 (0.35) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979397 0.95 NPC1 (0.35) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979357 0.93 NPC1 (0.37) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979312 0.93 DUSP3 (0.34) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979347 0.93 MAPK10 (0.35) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL17990550 0.90 L3MBTL1 (0.39) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979415 0.89 MAPK10 (0.33) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979391 0.89 MAPK10 (0.33) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14979434 0.89 CTDSP1 (0.37) NPC1RAB9ASMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
WO-2013073859-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-05-23 WO disclosed