SCHEMBL14979434

SCHEMBL14979434

Fc1cc(-c2ccc(-c3ccccc3)cc2)cc(-c2cnc(-n3c4ccccc4c4ccc5ccccc5c43)nc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NR3C1 P04150 1/20 0.34
CYP1A1 P04798 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP1B1 Q16678 2/20 0.33
PRKDC P78527 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
DHODH Q02127 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979401 0.94 NPC1 (0.35) NR3C1NPC1LMNAMAPTRECQL
SCHEMBL14979397 0.94 NPC1 (0.35) NR3C1NPC1LMNAMAPTRECQL
SCHEMBL14979432 0.91 NR3C1 (0.39) CTDSP1TDP1NR3C1CYP1A1CYP1A2
SCHEMBL14979314 0.91 FGFR1 (0.35) NR3C1CYP1A2NPC1LMNAMAPT
SCHEMBL14979357 0.91 NPC1 (0.37) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL14979358 0.89 NPC1 (0.35) CYP1A1CYP1B1NPC1LMNAMAPT
SCHEMBL17990550 0.87 L3MBTL1 (0.39) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL14979403 0.86 PDGFRB (0.39) CYP1A1CYP1A2CYP1B1MAPTKDM4E
SCHEMBL14979313 0.86 TNF (0.35) TDP1NPC1LMNAMAPTRECQL
SCHEMBL14979394 0.86 TNF (0.35) TDP1NPC1LMNAMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
WO-2013073859-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-05-23 WO disclosed