Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10257696 | 0.87 | ACACB (0.40) | TAAR1ACHEMTNR1AMTNR1BCYSLTR1 | |
| SCHEMBL22047298 | 0.82 | TAAR1 (0.49) | TAAR1ACHEAOC3MTNR1AMTNR1B | |
| SCHEMBL5477927 | 0.81 | TAAR1 (0.56) | TAAR1AOC3MTNR1AMTNR1B | |
| SCHEMBL611119 | 0.81 | TAAR1 (0.45) | TAAR1ACHE | |
| SCHEMBL10235916 | 0.76 | CYP2D6 (0.49) | — | |
| SCHEMBL6943329 | 0.76 | CYP4F2 (0.61) | CYSLTR2CYSLTR1 | |
| SCHEMBL612474 | 0.75 | TAAR1 (0.40) | TAAR1 | |
| SCHEMBL11167304 | 0.74 | NOS1 (0.43) | TAAR1MTNR1AMTNR1B | |
| SCHEMBL611495 | 0.73 | MAPK14 (0.38) | TAAR1ACHE | |
| SCHEMBL611494 | 0.73 | MAPK14 (0.38) | TAAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450527-B2 | Amine derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2013-05-28 | — | — | US | disclosed |