Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12881236 | 0.84 | ALOX5 (0.49) | TAAR1ACHEALOX5PPARGPPARA | |
| SCHEMBL14979585 | 0.82 | TAAR1 (0.42) | TAAR1ACHEAOC3MTNR1AMTNR1B | |
| SCHEMBL28121082 | 0.82 | TAAR1 (0.60) | TAAR1ACHE | |
| SCHEMBL28121086 | 0.82 | TAAR1 (0.60) | TAAR1ACHE | |
| SCHEMBL27987194 | 0.82 | TAAR1 (0.60) | TAAR1ACHE | |
| SCHEMBL5245979 | 0.81 | ALOX5 (0.47) | TAAR1ACHEALOX5PPARGPPARA | |
| SCHEMBL20233648 | 0.81 | CHRM2 (0.51) | ACHEALOX5MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL30230412 | 0.81 | CHRM2 (0.51) | ACHEALOX5MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL30230087 | 0.81 | CHRM2 (0.51) | ACHEALOX5MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL11167304 | 0.81 | NOS1 (0.43) | TAAR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2020-06-03 | — | — | EP | disclosed |