Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17082354 | 0.86 | FAAH (0.49) | FAAHLIPEGPR119MCHR1BCHE | |
| SCHEMBL14979618 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19LIPEPIK3CD | |
| SCHEMBL16866583 | 0.84 | FAAH (0.48) | FAAHLIPEGPR119MCHR1BCHE | |
| SCHEMBL518160 | 0.84 | FAAH (0.48) | FAAHCYP1A2 | |
| SCHEMBL13692025 | 0.84 | FAAH (0.47) | FAAHCYP1A2LIPEGPR119MCHR1 | |
| SCHEMBL14979622 | 0.80 | FAAH (0.59) | FAAHGPR119MCHR1 | |
| SCHEMBL14979623 | 0.80 | FAAH (0.57) | FAAHCYP1A2CYP2C9CYP2C19LIPE | |
| SCHEMBL28418487 | 0.80 | FAAH (0.54) | FAAHPIK3CDGPR119 | |
| SCHEMBL17074803 | 0.79 | FAAH (0.60) | FAAHMCHR1 | |
| SCHEMBL17082348 | 0.73 | CHRNA7 (0.41) | FAAHLIPEGPR119CHRNA7MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450346-B2 | Azetidine derivatives as FAAH inhibitors | VERNALIS (R&D) LTD. (GB) | 2013-05-28 | — | — | US | disclosed |