Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817635 | 0.74 | DNM1 (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7113540 | 0.72 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL14701675 | 0.72 | DNM1 (0.37) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1530922 | 0.72 | DNM1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5078489 | 0.72 | DNM1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL394606 | 0.70 | DNM1 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL28991670 | 0.69 | — | — | |
| SCHEMBL14701727 | 0.69 | — | — | |
| SCHEMBL17210714 | 0.69 | DNM1 (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL19571046 | 0.68 | SIGMAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450290-B2 | Methods for treating androgen receptor dependent disorders including cancers | ENZON PHARMACEUTICALS, INC. (US) | 2013-05-28 | — | — | US | disclosed |