SCHEMBL394606

SCHEMBL394606

NCCCCCCOP(N)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA3 P07451 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
BLM P54132 1/20 0.40
NFKB1 P19838 1/20 0.35
APP P05067 1/20 0.33
PAOX Q6QHF9 2/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23928729 0.97
SCHEMBL5078489 0.82 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL1530922 0.82 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL28991670 0.79
SCHEMBL9750691 0.78
SCHEMBL2563068 0.78 HTT (0.41) CA12CA1CA2CA3CA4
SCHEMBL18704189 0.78 HTT (0.41) CA12CA1CA2CA3CA4
SCHEMBL2843073 0.78
SCHEMBL8935552 0.78 HTT (0.41) CA12CA1CA2CA3CA4
SCHEMBL17210714 0.78 DNM1 (0.38) DNM1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3231446-B1 COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO SPECIFIC NEURON TYPES PALOMO LTD (CY) 2026-01-07 EP disclosed
EP-3350333-B2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNATX INC (US) 2025-08-06 EP disclosed
US-20250186624-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION ARES CAPITAL CORPORATION, AS AGENT 2025-06-12 US disclosed
US-12109274-B2 Polynucleotides containing a stabilizing tail region MODERNATX, INC. (US) 2024-10-08 US disclosed
EP-4159741-A1 METHOD FOR PRODUCING A CHIMERIC POLYNUCLEOTIDE ENCODING A POLYPEPTIDE HAVING A TRIAZOLE-CONTAINING INTERNUCLEOTIDE LINKAGE ModernaTX, Inc. (US) 2023-04-05 EP disclosed
EP-4101930-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION ModernaTX, Inc. (US) 2022-12-14 EP disclosed
EP-3169693-B1 CHIMERIC POLYNUCLEOTIDES MODERNATX INC (US) 2022-03-09 EP disclosed
EP-3350333-B1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNATX INC (US) 2021-10-27 EP disclosed
US-10407683-B2 Circular polynucleotides MODERNATX, INC. (US) 2019-09-10 US disclosed
EP-3169335-B1 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS INC (US) 2019-08-28 EP disclosed
US-20120115937-A1 Ghrelin binding nucleic acids NOXXON PHARMA AG (DE) 2012-05-10 US disclosed
US-8101734-B2 Ghrelin binding nucleic acids NOXXON PHARMA AG (DE) 2012-01-24 US disclosed
EP-1866412-A2 GHRELIN BINDING NUCLEIC ACIDS Noxxon Pharma AG (DE) 2007-12-19 EP disclosed
EP-0878554-B1 Detection of nucleic acids by fluorescence quenching BECTON DICKINSON CO (US) 2007-02-21 EP disclosed
US-20060258607-A1 Ghrelin binding nucleic acids NOXXON PHARMA AG (DE) 2006-11-16 US disclosed
WO-2006108599-A2 GHRELIN BINDING NUCLEIC ACIDS NOXXON PHARMA AG (DE) 2006-10-19 WO disclosed
US-6054279-A Detection of nucleic acids by fluorescence quenching BECTON DICKINSON AND COMPANY (US) 2000-04-25 US disclosed
US-5919630-A USING A OLIGONUCLEOTIDE DETECTOR BECTON, DICKINSON AND COMPANY (US) 1999-07-06 US disclosed
US-5846726-A Detection of nucleic acids by fluorescence quenching BECTON, DICKINSON AND COMPANY (US) 1998-12-08 US disclosed
EP-0878554-A2 Detection of nucleic acids by fluorescence quenching Becton, Dickinson and Company (US) 1998-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258607-A1 Ghrelin binding nucleic acids IGF2BP1, IGF2BP3, CRHBP DNM1 1725/4885CA12 3400/4885CA1 3423/4885
US-10407683-B2 Circular polynucleotides POLN, POLRMT, POLI DNM1 1372/4885CA12 3226/4885CA1 4719/4885
US-20120115937-A1 Ghrelin binding nucleic acids IGF2BP1, IGF2BP3, CRHBP DNM1 1725/4885CA12 3400/4885CA1 3423/4885
US-12109274-B2 Polynucleotides containing a stabilizing tail region POLR2E, POLN, PHAX DNM1 1677/4885CA12 4728/4885CA1 4822/4885
US-20250186624-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION POLR2E, POLN, PHAX DNM1 1677/4885CA12 4728/4885CA1 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.