Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | FYN | P06241 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31431633 | 0.87 | ERN1 (0.64) | TNFRSF1AFYNMAOAMAOBERN1 | |
| SCHEMBL4121356 | 0.87 | ERN1 (0.64) | TNFRSF1AFYNMAOAMAOBERN1 | |
| SCHEMBL430038 | 0.86 | TUBB4A (0.59) | TNFRSF1AFYNTSHR | |
| SCHEMBL10316407 | 0.85 | FYN (0.60) | TNFRSF1AALDH1A1MAPTPOLBABCB1 | |
| SCHEMBL10227283 | 0.81 | TUBB4A (0.54) | TNFRSF1AMAPTFYN | |
| SCHEMBL4114637 | 0.81 | BRAF (0.61) | ALDH1A1POLBERN1BRAF | |
| SCHEMBL10389918 | 0.80 | MAP4K4 (0.59) | ALDH1A1MAPTFYNMEN1KMT2A | |
| SCHEMBL12599367 | 0.80 | ALDH1A1 (0.56) | TNFRSF1AALDH1A1MAPTPOLBGFER | |
| SCHEMBL2552382 | 0.80 | TNFRSF1A (0.61) | TNFRSF1AALDH1A1ABCB1FYNERN1 | |
| SCHEMBL4424350 | 0.80 | CYP1A1 (0.63) | ALDH1A1ABCB1FYNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074834-A1 | FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF | SAREPTA THERAPEUTICS, INC. (US) | 2013-05-23 | — | — | WO | disclosed |