Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27586476 | 0.99 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2APDE4DMAPT | |
| SCHEMBL1616095 | 0.88 | STIM1 (0.54) | PDE4DERN1RAB9ALMNAFNTA | |
| SCHEMBL27736223 | 0.87 | FYN (0.55) | ALDH1A1MEN1KMT2APDE4DFYN | |
| SCHEMBL1617752 | 0.87 | ERN1 (0.51) | ALDH1A1MEN1KMT2AMAPTERN1 | |
| SCHEMBL1617949 | 0.87 | ERN1 (0.46) | ALDH1A1MEN1KMT2APDE4DFYN | |
| SCHEMBL14765630 | 0.83 | ERN1 (0.43) | ALDH1A1MEN1KMT2APDE4DFYN | |
| SCHEMBL6769062 | 0.81 | ERN1 (0.48) | ALDH1A1MEN1KMT2AMAPTERN1 | |
| SCHEMBL14980439 | 0.80 | TNFRSF1A (0.65) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL4602476 | 0.79 | ERN1 (0.50) | ALDH1A1PDE4DERN1LMNAGAA | |
| SCHEMBL8845578 | 0.79 | HDAC4 (0.62) | ALDH1A1MEN1KMT2APDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152291-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152291-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | SELP, SELL, SELE | ALDH1A1 328/4885MEN1 4309/4885KMT2A 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.