SCHEMBL7942685 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	STAT6	P42226	2/20	0.47

▸	KDM5A	P29375	1/20	0.40

▸	CYP51A1	Q16850	1/20	0.40

▸	AKR1C3	P42330	4/20	0.39

▸	DRD2	P14416	1/20	0.39

▸	CCKBR	P32239	1/20	0.39

▸	ELANE	P08246	2/20	0.38

▸	F2	P00734	1/20	0.37

▸	F10	P00742	1/20	0.37

▸	PLG	P00747	1/20	0.37

▸	PRSS1	P07477	1/20	0.37

▸	HRH4	Q9H3N8	1/20	0.37

▸	HSPA5	P11021	1/20	0.36

▸	HSPA8	P11142	1/20	0.36

▸	HSPA9	P38646	1/20	0.36

▸	HSPA2	P54652	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14980442	0.89	STAT6 (0.48)	STAT6CYP51A1AKR1C3DRD2CCKBR
SCHEMBL7934440	0.89	STAT6 (0.48)	STAT6CYP51A1AKR1C3DRD2CCKBR
SCHEMBL7942137	0.88	STAT6 (0.41)	STAT6KDM5ACYP51A1AKR1C3DRD2
SCHEMBL14980460	0.88	STAT6 (0.41)	STAT6KDM5ACYP51A1AKR1C3DRD2
SCHEMBL14980527	0.88	CYP51A1 (0.41)	STAT6KDM5ACYP51A1AKR1C3DRD2
SCHEMBL7934126	0.87	STAT6 (0.48)	STAT6CYP51A1AKR1C3DRD2CCKBR
SCHEMBL7933189	0.87	STAT6 (0.42)	STAT6KDM5ACYP51A1CCKBR
SCHEMBL14980528	0.86	STAT6 (0.40)	STAT6KDM5ACYP51A1AKR1C3DRD2
SCHEMBL1930560	0.85	DRD2 (0.41)	STAT6KDM5ACYP51A1AKR1C3DRD2
SCHEMBL19856970	0.85	DRD2 (0.41)	STAT6KDM5ACYP51A1AKR1C3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010011914-A1	TRPV4 ANTAGONISTS	SMITHKLINE BEECHAM CORPORATION (US)	2010-01-28	—	—	WO	disclosed