Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936426 | 0.94 | STAT6 (0.50) | STAT6CYP51A1DRD2AKR1C3CCKBR | |
| SCHEMBL7934126 | 0.92 | STAT6 (0.48) | STAT6CYP51A1DRD2AKR1C3CCKBR | |
| SCHEMBL7945427 | 0.91 | STAT6 (0.45) | STAT6CYP51A1DRD2AKR1C3CCKBR | |
| SCHEMBL7941160 | 0.91 | STAT6 (0.45) | STAT6CYP51A1DRD2DRD3CCKBR | |
| SCHEMBL14980442 | 0.89 | STAT6 (0.48) | STAT6CYP51A1DRD2AKR1C3CCKBR | |
| SCHEMBL7934440 | 0.89 | STAT6 (0.48) | STAT6CYP51A1DRD2AKR1C3CCKBR | |
| SCHEMBL7941165 | 0.89 | STAT6 (0.46) | STAT6NPC1RAB9ACYP51A1DRD2 | |
| SCHEMBL7941162 | 0.86 | STAT6 (0.45) | STAT6CYP51A1DRD2CCKBR | |
| SCHEMBL19856950 | 0.85 | NPC1 (0.47) | STAT6NPC1RAB9ACYP51A1DRD2 | |
| SCHEMBL19856951 | 0.85 | NPC1 (0.47) | STAT6NPC1RAB9ACYP51A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011912-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |