Azelaic Acid

Azelaic Acid

SCHEMBL1498058

O=C([O-])CCCCCCCC(=O)[O-].O=C([O-])CCCCCCCC(=O)[O-].O=C([O-])CCCCCCCC(=O)[O-].[Fe+3].[Fe+3]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.55
FABP3 P05413 9/20 0.52
FFAR3 O14843 2/20 0.47
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11668421 1.00 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
Adipic Acid SCHEMBL1194226 0.96 CA1 (0.58) CA1FABP3FFAR3HDAC3HDAC1
Octanedioate SCHEMBL8386996 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
Sebacic Acid SCHEMBL6562957 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
Azelaic Acid SCHEMBL11428758 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
Azelaic Acid SCHEMBL3975767 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
SCHEMBL11046980 0.93 CA1 (0.63) CA1FABP3FFAR3HDAC3HDAC1
Sebacic Acid SCHEMBL3936260 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
Sebacic Acid SCHEMBL847655 0.93 CA1 (0.55) CA1FABP3FFAR3HDAC3HDAC1
SCHEMBL20577558 0.93 CA1 (0.63) CA1FABP3FFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738068-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates Centre National de la Recherche Scientifique—CNRS (FR) 2020-08-11 US disclosed
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-12-06 US disclosed
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2018-09-04 US disclosed
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST Centre National De La Recherche Scientifique - CNR S (FR) 2011-03-03 US disclosed
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS- (FR) 2010-09-09 US disclosed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 US disclosed
US-4225661-A DIAZO RESIN LAYER, PHOTOCHROMIC DYE AND ADDITION POLYMER OVERLAYER THE RICHARDSON COMPANY (US) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST MITF, SLCO2B1, SLCO2A1 CA1 90/4885FABP3 424/4885FFAR3 883/4885
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE SLCO2A1, SLCO4C1, SLCO2B1 CA1 898/4885FABP3 1234/4885FFAR3 3353/4885
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates SLC39A3, SLC40A1, AOC3 CA1 657/4885FABP3 110/4885FFAR3 594/4885
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 CA1 644/4885FABP3 110/4885FFAR3 587/4885
US-10738068-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates SLC40A1, FECH, FTH1 CA1 441/4885FABP3 418/4885FFAR3 1805/4885
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 CA1 657/4885FABP3 110/4885FFAR3 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.