Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980601 | 0.96 | ALOX15 (0.42) | ALOX15SIGMAR1ACE2KDM4EALDH1A1 | |
| SCHEMBL29041543 | 0.90 | ALOX15 (0.62) | ALOX15SIGMAR1ACE2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3672217 | 0.88 | ALOX15 (0.59) | ALOX15SIGMAR1ACE2ALDH1A1 | |
| SCHEMBL14980602 | 0.83 | ACE2 (0.50) | ALOX15SIGMAR1ACE2 | |
| SCHEMBL16075891 | 0.79 | ALDH1A1 (0.45) | ALOX15SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL15065348 | 0.79 | ALDH1A1 (0.50) | ALOX15KDM4EALDH1A1 | |
| Lindane SCHEMBL3672215 | 0.79 | ALOX15 (0.48) | ALOX15SIGMAR1ACE2ALDH1A1 | |
| SCHEMBL14980600 | 0.79 | ACE2 (0.63) | ALOX15SIGMAR1ACE2KDM4EALDH1A1 | |
| SCHEMBL17705625 | 0.79 | ALOX15 (0.43) | ALOX15SIGMAR1ACE2 | |
| SCHEMBL19072067 | 0.78 | ALOX15 (0.52) | ALOX15SIGMAR1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-23 | — | — | US | disclosed |
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | ALOX15 48/4885SIGMAR1 2319/4885ACE2 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.