⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803017 | 0.86 | ALDH1A1 (0.35) | — | |
| Bromide SCHEMBL29657994 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL31460438 | 0.76 | NFKB1 (0.39) | — | |
| SCHEMBL4654571 | 0.74 | DNM1 (0.42) | — | |
| SCHEMBL28733275 | 0.72 | NFKB1 (0.35) | — | |
| SCHEMBL23853045 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL25465590 | 0.63 | — | — | |
| SCHEMBL8182 | 0.61 | — | — | |
| SCHEMBL16345592 | 0.61 | NFKB1 (0.75) | — | |
| SCHEMBL7267804 | 0.61 | NFKB1 (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-23 | — | — | US | disclosed |
| US-8969353-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLO (US) | 2014-10-30 | — | — | US | disclosed |
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |