SCHEMBL14980865

SCHEMBL14980865

CO[Si](CCCSC(=S)SCc1ccccc1)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.43
HDAC4 P56524 3/20 0.43
HDAC1 Q13547 3/20 0.43
HDAC7 Q8WUI4 3/20 0.43
HDAC2 Q92769 3/20 0.43
HDAC10 Q969S8 3/20 0.43
HDAC11 Q96DB2 3/20 0.43
HDAC8 Q9BY41 3/20 0.43
HDAC6 Q9UBN7 3/20 0.43
HDAC9 Q9UKV0 3/20 0.43
HDAC5 Q9UQL6 3/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
IDO1 P14902 4/20 0.37
NOS1 P29475 2/20 0.37
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14961194 0.87 HDAC3 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2338466 0.86 HDAC3 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL17785530 0.81 LMNA (0.33) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL14961196 0.80 HDAC3 (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL26992717 0.79 IDO1 (0.46) CA12CA1CA2CA9IDO1
SCHEMBL26992747 0.79 IDO1 (0.53) CA12CA1CA2CA9IDO1
SCHEMBL14980906 0.79 CYP2C19 (0.46) ALDH1A1MEN1KMT2A
SCHEMBL10966466 0.79 HDAC3 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL261767 0.76 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16774671 0.76 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115672261-B Sulfhydryl Schiff base side group-containing polymer modified attapulgite and preparation method thereof 江苏海洋大学 2024-02-20 CN claimed
CN-115672261-A Polymer-modified attapulgite containing sulfhydryl Schiff base side group and preparation method thereof 江苏海洋大学 2023-02-03 CN claimed
CN-114015062-A Preparation method of photoresponse type polydopamine-coated cellulose nanocrystal 陕西科技大学 2022-02-08 CN claimed
CN-115672261-B Sulfhydryl Schiff base side group-containing polymer modified attapulgite and preparation method thereof 江苏海洋大学 2024-02-20 CN disclosed
CN-115672261-A Polymer-modified attapulgite containing sulfhydryl Schiff base side group and preparation method thereof 江苏海洋大学 2023-02-03 CN disclosed
CN-114015062-A Preparation method of photoresponse type polydopamine-coated cellulose nanocrystal 陕西科技大学 2022-02-08 CN disclosed
US-9822330-B2 Light-degradable material, substrate, and method for patterning the substrate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-21 US disclosed
US-20150267159-A1 LIGHT-DEGRADABLE MATERIAL, SUBSTRATE, AND METHOD FOR PATTERNING THE SUBSTRATE UNIVERSITY OF TOYAMA (JP) 2015-09-24 US disclosed
EP-2596963-B1 Functionalized polymer, rubber composition with such a polymer and pneumatic tire GOODYEAR TIRE & RUBBER (US) 2014-07-02 EP disclosed
EP-2596963-A1 Functionalized polymer, rubber composition with such a polymer and pneumatic tire The Goodyear Tire & Rubber Company (US) 2013-05-29 EP disclosed