SCHEMBL261767

SCHEMBL261767

CCCCCCCCCCCCSC(=S)SCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC7 Q8WUI4 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC11 Q96DB2 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC9 Q9UKV0 2/20 0.47
HDAC5 Q9UQL6 2/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
EPHX2 P34913 2/20 0.41
PKM P14618 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
IDO1 P14902 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13583967 1.00 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16774671 1.00 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10966466 0.93 HDAC3 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL15809672 0.92 ESR1 (0.39) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1170413 0.89 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8514707 0.86 CA12 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL21826727 0.84 NOS1 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5575000 0.81 HDAC3 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18717251 0.81 MEN1 (0.41) CA12CA1CA2CA9EPHX2
SCHEMBL161188 0.80 CA12 (0.65) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443482-B1 BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. BAUSCH & LOMB (US) 2017-03-01 EP claimed
CN-102460223-B Biomedical devices BAUSCH & LOMB 2014-04-16 CN claimed
CN-102460223-A Biomedical devices BAUSCH & LOMB 2012-05-16 CN claimed
EP-2443482-A2 BIOMEDICAL DEVICES Bausch & Lomb Incorporated (US) 2012-04-25 EP claimed
WO-2010147864-A2 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2010-12-23 WO claimed
US-20100315588-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US claimed
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2026-05-28 US disclosed
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES BAUSCH & LOMB IRELAND LTD (IE) 2026-03-19 US disclosed
EP-4646240-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING Bausch + Lomb Ireland Limited (IE) 2025-11-12 EP disclosed
US-20250321364-A1 SURFACE MODIFIED OPHTHALMIC DEVICES BAUSCH & LOMB IRELAND LTD (IE) 2025-10-16 US disclosed
WO-2025215096-A1 SILICONE CONTACT LENS-FORMING PREPOLYMER AND SILICONE CONTACT LENS FORMED THEREFROM BAUSCH + LOMB IRELAND LIMITED (IE) 2025-10-16 WO disclosed
CN-119907844-A Adhesive composition and adhesive sheet 株式会社力森诺科 2025-04-29 CN disclosed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
US-7625985-B1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-12-01 US disclosed
US-20070149709-A1 S-benzyl-S'-(11-undecanoic acid) trithiocarbonate as free radical control agent; butadiene-styrene-vinylpyridine copolymer GOODYEAR TIRE & RUBBER COMPANY, THE 2007-06-28 US disclosed
US-20070149741-A1 FUNCTIONAL TRITHIOCARBONATE RAFT AGENTS GOODYEAR TIRE & RUBBER COMPANY, THE 2007-06-28 US disclosed
EP-1801137-A1 Surfactantless synthesis of amphiphilic cationic block copolymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed
EP-1801100-A1 Functional trithiocarbonate RAFT agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed
EP-1801158-A1 Water-based process for the preparation of polymer-clay nanocomposites THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed
US-7230063-B1 Functional trithiocarbonate RAFT agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES CRYAA, CRYAB, CRYZ HDAC3 993/4885HDAC4 225/4885HDAC1 678/4885
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES EPCAM, STIM1, SMCHD1 HDAC3 1277/4885HDAC4 710/4885HDAC1 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.