Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488828 | 0.89 | CYP1A2 (0.49) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17354073 | 0.86 | CYP1A2 (0.47) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12761207 | 0.85 | LMNA (0.39) | SMN1; SMN2MAPTALDH1A1LMNAHTT | |
| SCHEMBL14961195 | 0.85 | CYP2C19 (0.45) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1408863 | 0.84 | CYP2C19 (0.37) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6073782 | 0.83 | CYP2C19 (0.44) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14980865 | 0.79 | HDAC3 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14436868 | 0.79 | LMNA (0.42) | CYP3A4SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL11727360 | 0.78 | CYP1A2 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12960343 | 0.77 | HRH3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596963-B1 | Functionalized polymer, rubber composition with such a polymer and pneumatic tire | GOODYEAR TIRE & RUBBER (US) | 2014-07-02 | — | — | EP | disclosed |
| EP-2596963-A1 | Functionalized polymer, rubber composition with such a polymer and pneumatic tire | The Goodyear Tire & Rubber Company (US) | 2013-05-29 | — | — | EP | disclosed |