Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1498089

[Cl-].c1ccc([C+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.33
ALDH1A1 P00352 5/20 0.38
TSHR P16473 4/20 0.33
TDP1 Q9NUW8 4/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ALOX12 P18054 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
NOTUM Q6P988 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395660 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1CA1CA2
Fluoride Ion SCHEMBL3891341 0.92 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL29130047 0.83 CYP3A4 (0.33) ALDH1A1TDP1CA4CA14CA7
SCHEMBL30572496 0.83 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL2863077 0.83 CYP3A4 (0.33) ALDH1A1TDP1CA4CA14CA7
SCHEMBL3292756 0.83 ALDH1A1 (0.39) ALDH1A1TSHRACHEALOX15
SCHEMBL3984229 0.83 TSHR (0.35) ALDH1A1TSHRLMNABBOX1EHMT2
SCHEMBL4817504 0.78 CYP3A4 (0.30) TDP1CYP3A4
SCHEMBL30437274 0.76 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA1CA2
Hydrochloric Acid SCHEMBL10747097 0.74 ALDH1A1 (0.65) ALDH1A1TSHRTDP1ALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048388-A1 TRIPHENYLCARBENIUM SALTS OF GROUP 13 FLUOROARYL COMPLEXES DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-06-10 WO claimed
WO-2017099956-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-06-15 WO disclosed
US-20170158981-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
WO-2011032681-A1 LIPOPHILIC METALLATES Universität Heidelberg (DE) 2011-03-24 WO disclosed
US-7901074-B2 Lens for safety glasses YAMAMOTO KOGAKU CO., LTD. (JP) 2011-03-08 US disclosed
EP-1979361-B1 OXONIUM AND SULFONIUM SALTS MERCK PATENT GMBH (DE) 2010-11-24 EP disclosed
EP-2253638-A2 Fluoralkylfluorophosphate salts Merck Patent GmbH (DE) 2010-11-24 EP disclosed
US-7585991-B2 (Pentafluorophenyl) group 11 and 12 metal compounds, processes for preparing (pentafluorophenyl) group 11 and 12 metal compounds, and uses thereof LEWIS STEWART P 2009-09-08 US disclosed
EP-1979361-A2 OXONIUM AND SULFONIUM SALTS Merck Patent GmbH (DE) 2008-10-15 EP disclosed
US-20080177015-A1 (Pentafluorophenyl) group 11 and 12 metal compounds, processes for preparing (pentafluorophenyl) group 11 and 12 metal compounds, and uses thereof LEWIS STEWART P 2008-07-24 US disclosed
WO-2002012154-A2 CATALYST SYSTEM FOR THE POLYMERISATION OF OLEFINS BAYER AKTIENGESELLSCHAFT (DE) 2002-02-14 WO disclosed
US-20020010079-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2002-01-24 US disclosed
US-6281389-B1 MIXING WITH SOLVENT; DISTILLATION NIPPON SHOKUBAI CO., LTD. (JP) 2001-08-28 US disclosed
EP-1066329-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-01-10 EP disclosed
EP-1066302-A1 CYCLOPENTADIENYL TRANSITION METAL COMPOUNDS, AS POLYMERIZATION CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2001-01-10 EP disclosed
US-6100414-A Cyclopentadienyl transition metal compounds useful as polymerization catalysts EASTMAN CHEMICAL COMPANY (US) 2000-08-08 US disclosed
EP-0985672-A2 Method for purifying tetrakis(fluoroaryl)borate compounds Nippon Shokubai Co., Ltd. (JP) 2000-03-15 EP disclosed
WO-1999051615-A1 CYCLOPENTADIENYL TRANSITION METAL COMPOUNDS, AS POLYMERIZATION CATALYSTS EASTMAN CHEMICAL COMPANY (US) 1999-10-14 WO disclosed
WO-1999050311-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1999-10-07 WO disclosed
US-4206067-A Thermally stabilized erosion-inhibited functional fluids containing perhalometal compounds and an organic base CHEVRON RESEARCH COMPANY (US) 1980-06-03 US disclosed