SCHEMBL17354073

SCHEMBL17354073

CO[Si](CCCSCCc1ccccc1)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CA2 P00918 2/20 0.39
CES1 P23141 2/20 0.37
ALPL P05186 1/20 0.36
ALPI P09923 1/20 0.36
ALPG P10696 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX5 P09917 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17354072 0.87 CALM1 (0.45) SMN1; SMN2TDP1L3MBTL1ALDH1A1
SCHEMBL16352360 0.87 ALDH1A1 (0.48) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL14980906 0.86 CYP2C19 (0.46) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL14090594 0.85 MMP12 (0.35) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL15806052 0.84 MAPT (0.41) CA2SMN1; SMN2ALDH1A1MAPT
SCHEMBL2822247 0.83 IDO1 (0.45) TDP1L3MBTL1ALDH1A1
SCHEMBL17354069 0.83 CYP1A2 (0.44) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL2748794 0.82 L3MBTL1 (0.47) TDP1L3MBTL1
SCHEMBL15806048 0.81 RCE1 (0.35) CA2ALDH1A1
SCHEMBL17354078 0.81 PPARA (0.34) TDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111232989-B Silicon-based benzene compound containing multi-alkoxy groups and hybrid silica aerogel 佛山市农芯智能科技有限公司 2023-01-20 CN disclosed
CN-111232989-A Silicon-based benzene compound containing multi-alkoxy groups and hybrid silica aerogel 洪永建 2020-06-05 CN disclosed
US-9217921-B2 Resist underlayer film forming composition containing silicon having sulfide bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-22 US disclosed