Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13398104 | 0.89 | POLB (0.43) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3316993 | 0.86 | NPC1 (0.44) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14980935 | 0.85 | PLK1 (0.44) | POLBNPC1RAB9AALDH1A1EPHX2 | |
| SCHEMBL3318810 | 0.85 | ALDH1A1 (0.47) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4112246 | 0.84 | NPC1 (0.41) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13397812 | 0.84 | ALDH1A1 (0.44) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3314282 | 0.84 | ALDH1A1 (0.44) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17296893 | 0.83 | ATM (0.53) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13398073 | 0.82 | NPC1 (0.39) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3315274 | 0.81 | MAPK1 (0.45) | NPC1RAB9AALDH1A1EPHX2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |