Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318810 | 0.97 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL4112246 | 0.89 | NPC1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13398104 | 0.88 | POLB (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13871223 | 0.87 | SMN1; SMN2 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13398073 | 0.87 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3312931 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3317005 | 0.85 | ADCY1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3317029 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3314780 | 0.84 | FKBP1A (0.42) | ALDH1A1SMN1; SMN2HPGDNAAALMNA | |
| SCHEMBL14980937 | 0.84 | POLB (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199934-B2 | Alpha-hydroxyketones | BASF SE (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20100104979-A1 | ALPHA-HYDROXYKETONES | IGM GROUP B.V. (NL) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104979-A1 | ALPHA-HYDROXYKETONES | C9, C1R, CBR3 | ALDH1A1 734/4885NPC1 3402/4885RAB9A 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.