Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315409 | 0.93 | ALDH1A1 (0.47) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL17296896 | 0.91 | ALDH1A1 (0.54) | HPGDALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL3320774 | 0.88 | ALDH1A1 (0.43) | HPGDALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL3317429 | 0.87 | ALDH1A1 (0.41) | HPGDALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL13417396 | 0.86 | SMN1; SMN2 (0.44) | HPGDALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL3315274 | 0.80 | MAPK1 (0.45) | ALDH1A1GAAEPHX2CNR2 | |
| SCHEMBL17296893 | 0.79 | ATM (0.53) | ALDH1A1POLBKMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL14980948 | 0.79 | NPC1 (0.46) | ALDH1A1POLBEPHX2CNR2 | |
| SCHEMBL14980935 | 0.77 | PLK1 (0.44) | HPGDALDH1A1POLBKMT2AEPHX2 | |
| SCHEMBL17296899 | 0.76 | MEN1 (0.46) | HPGDALDH1A1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |