Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | BLM | P54132 | 4/20 | 0.67 |
| ▸ | APP | P05067 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | APAF1 | O14727 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | ITGAM | P11215 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848654 | 0.96 | MEN1 (0.68) | MEN1KMT2AHTTBLMAPP | |
| SCHEMBL18070361 | 0.96 | MEN1 (0.68) | MEN1KMT2AHTTBLMAPP | |
| Iodide SCHEMBL7546369 | 0.86 | APP (0.66) | MEN1KMT2AHTTBLMAPP | |
| SCHEMBL14984251 | 0.85 | KMT2A (0.63) | MEN1KMT2AHTTBLMAPP | |
| SCHEMBL27391249 | 0.84 | PRMT1 (0.75) | MEN1KMT2AHTTBLMAPP | |
| Iodide SCHEMBL9551890 | 0.81 | MEN1 (0.57) | MEN1KMT2AHTTBLMAPP | |
| Alazanine SCHEMBL1506901 | 0.80 | MEN1 (1.00) | MEN1KMT2AHTTBLMAPP | |
| Alazanine SCHEMBL30133356 | 0.80 | MEN1 (1.00) | MEN1KMT2AHTTBLMAPP | |
| Alazanine SCHEMBL12364489 | 0.80 | MEN1 (1.00) | MEN1KMT2AHTTBLMAPP | |
| Alazanine SCHEMBL10020546 | 0.80 | MEN1 (1.00) | MEN1KMT2AHTTBLMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280921-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | CRYAA, CRYAB, HSPH1 | MEN1 3941/4885KMT2A 4553/4885HTT 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.