Alazanine

Alazanine

SCHEMBL10020546

CCN1/C(=C/C=C/c2sc3ccccc3[n+]2CC)Sc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
HTT P42858 4/20 1.00
BLM P54132 4/20 1.00
APP P05067 7/20 0.98
NPC1 O15118 5/20 0.98
RAB9A P51151 5/20 0.98
APAF1 O14727 2/20 0.98
ITGB2 P05107 1/20 0.98
ALPL P05186 1/20 0.98
ITGAM P11215 1/20 0.98
GFER P55789 1/20 0.98
L3MBTL1 Q9Y468 1/20 0.98
ALDH1A1 P00352 2/20 0.90
POLB P06746 2/20 0.90
MAPT P10636 2/20 0.90
THRB P10828 2/20 0.90
PKM P14618 2/20 0.90
RECQL P46063 2/20 0.90
SMN1; SMN2 Q16637 2/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alazanine SCHEMBL12364489 1.00 MEN1 (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL1506900 1.00 MEN1 (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL30133356 1.00 MEN1 (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL1506901 1.00 MEN1 (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL142862 0.99 APP (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL11690918 0.99 MEN1 (0.98) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL29887077 0.99 APP (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL31179678 0.99 MEN1 (0.98) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL29556313 0.99 APP (1.00) MEN1KMT2AHTTBLMAPP
Alazanine SCHEMBL5453750 0.99 APP (1.00) MEN1KMT2AHTTBLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) 2023-11-23 US disclosed
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 US disclosed
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 US disclosed
US-20170259541-A1 SHRINK FILMS, AND METHODS OF MAKING THEREOF DOW GLOBAL TECHNOLOGIES LLC 2017-09-14 US disclosed
US-9465290-B2 Near-infrared absorbing film compositions GLOBALFOUNDRIES INC. (KY) 2016-10-11 US disclosed
US-20150338417-A1 BINDING DOMAIN MAPPING GEORGE MASON UNIVERSITY 2015-11-26 US disclosed
US-20140210034-A1 NEAR-INFRARED ABSORBING FILM COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-31 US disclosed
US-8772376-B2 Near-infrared absorbing film compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-08 US disclosed
US-8722076-B2 Photochrome- or near IR dye-coupled polymeric matrices for medical articles SURMODICS, INC. (US) 2014-05-13 US disclosed
US-8722076-B2 Photochrome- or near IR dye-coupled polymeric matrices for medical articles SURMODICS, INC. (US) 2014-05-13 US disclosed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 US disclosed
US-20080316480-A1 AGGREGATES OF PLURAL TRANSITION METAL NANOPARTICLES AND PLURAL CYANINE DYE MOLECULES RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-12-25 US disclosed
US-20080316480-A1 AGGREGATES OF PLURAL TRANSITION METAL NANOPARTICLES AND PLURAL CYANINE DYE MOLECULES RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-12-25 US disclosed
US-20080275224-A1 Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes MERCK PATENT GMBH (DE) 2008-11-06 US disclosed
US-20080220436-A1 METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES INVESTIGEN, INC. 2008-09-11 US disclosed
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2008-08-28 US disclosed
US-20080108677-A1 Thioxothiazolidinone Compounds For Use As Pharmaceuticals KARYON-CTT LTD (FI) 2008-05-08 US disclosed
US-20080096193-A1 Methods and compositions for detecting polynucleotides INVESTIGEN, INC. 2008-04-24 US disclosed
US-20070231821-A1 Methods and compositions for detecting polynucleotides INVESTIGEN, INC. 2007-10-04 US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 MEN1 1539/4885KMT2A 3036/4885HTT 1743/4885
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA TFAM, COX5A, UQCRC1 MEN1 2633/4885KMT2A 3675/4885HTT 2179/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 MEN1 1647/4885KMT2A 3091/4885HTT 1730/4885
US-20070231821-A1 Methods and compositions for detecting polynucleotides POLN, POLRMT, POLH MEN1 3712/4885KMT2A 4752/4885HTT 141/4885
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor MAVS, EIF2AK2, BLVRB MEN1 4451/4885KMT2A 1614/4885HTT 2552/4885
US-20080275224-A1 Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes ZAP70, MYLK3, KIT MEN1 4104/4885KMT2A 823/4885HTT 3056/4885
US-20080096193-A1 Methods and compositions for detecting polynucleotides POLN, POLRMT, POLH MEN1 3230/4885KMT2A 4706/4885HTT 164/4885
US-20080108677-A1 Thioxothiazolidinone Compounds For Use As Pharmaceuticals ITGAM, ITGB1, ITGA1 MEN1 4099/4885KMT2A 2994/4885HTT 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.