Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984325 | 0.82 | SMN1; SMN2 (0.45) | CYP4F2CYP4A11SMN1; SMN2TOP2AMAPT | |
| SCHEMBL244299 | 0.79 | LTA4H (0.41) | CYP4F2CYP4A11POLBLTA4HCFTR | |
| SCHEMBL14984330 | 0.77 | CFTR (0.41) | SMN1; SMN2CFTRMAPTMMP8TRPM8 | |
| SCHEMBL2773061 | 0.69 | CYP4F2 (0.68) | CYP4F2CYP4A11LTA4HALOX5 | |
| Ethyl 3-Phenylpropanoate SCHEMBL304816 | 0.69 | TDP1 (0.75) | CYP4F2CYP4A11SMN1; SMN2ALOX5MAPT | |
| SCHEMBL25371019 | 0.68 | LTA4H (0.44) | LTA4HSMN1; SMN2TOP2AALOX5MAPT | |
| Ethyl 3-Phenylpropanoate SCHEMBL7440447 | 0.67 | TDP1 (0.72) | CYP4F2CYP4A11SMN1; SMN2ALOX5MAPT | |
| SCHEMBL69660 | 0.67 | CYP4F2 (0.86) | CYP4F2CYP4A11SMN1; SMN2ALOX5MAPT | |
| SCHEMBL260297 | 0.66 | ALOX5 (0.76) | CYP4F2CYP4A11POLBSMN1; SMN2ALOX5 | |
| SCHEMBL3393059 | 0.66 | POLB (0.71) | POLBALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156822-B2 | Functionally selective ligands of dopamine D2 receptors | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-10-13 | — | — | US | disclosed |
| US-20130137679-A1 | Novel Functionally Selective Ligands of Dopamine D2 Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137679-A1 | Novel Functionally Selective Ligands of Dopamine D2 Receptors | DRD2, AVPR2, NTSR2 | CYP4F2 2028/4885CYP4A11 3028/4885POLB 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.