Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825197 | 0.83 | CA1 (0.50) | HTTCA1CA2CA4CA9 | |
| SCHEMBL10124052 | 0.80 | CA1 (0.67) | HTTCA1CA2CA4CA9 | |
| SCHEMBL18851194 | 0.79 | HTT (0.55) | HTTCA1CA2CA4CA9 | |
| SCHEMBL10124295 | 0.73 | KMT2A (0.44) | KMT2AGAASMN1; SMN2RAB9AGALR3 | |
| SCHEMBL18825250 | 0.72 | HTT (0.57) | HTTCA1CA2CA4CA9 | |
| SCHEMBL14977309 | 0.71 | KMT2A (0.55) | KMT2AGAASMN1; SMN2RAB9AGALR3 | |
| SCHEMBL2512530 | 0.71 | CA1 (0.67) | HTTCA1CA2CA4CA9 | |
| SCHEMBL10124062 | 0.71 | CA1 (0.55) | HTTCA1CA2CA4CA9 | |
| SCHEMBL18850709 | 0.70 | HTT (0.54) | HTTCA1CA2CA4CA9 | |
| SCHEMBL10612189 | 0.70 | L3MBTL1 (0.43) | RAB9AOPRM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |