Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073043 | 0.86 | NAMPT (1.00) | NAMPTSMN1; SMN2TSHRMAPTHTT | |
| SCHEMBL14975698 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2242298 | 0.79 | SMN1; SMN2 (0.74) | NAMPTSMN1; SMN2TSHRMAPTHTT | |
| SCHEMBL14985303 | 0.78 | PKM (0.76) | SMN1; SMN2MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL14985298 | 0.76 | MAPT (0.68) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL14985280 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL14976194 | 0.76 | LMNA (0.67) | SMN1; SMN2MAPTHTTL3MBTL1MEN1 | |
| SCHEMBL11446232 | 0.75 | KMT2A (0.67) | SMN1; SMN2L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL14976630 | 0.75 | KMT2A (0.63) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL8401808 | 0.75 | TP53 (0.70) | SMN1; SMN2TSHRMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |