Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361478 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL683930 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL7143077 | 0.81 | NFKB1 (0.57) | ALDH1A1LMNATAAR1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL5108645 | 0.80 | GAA (0.47) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL4991770 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1LMNASMN1; SMN2TNFHSD17B10 | |
| SCHEMBL12018292 | 0.79 | KDM4E (0.44) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL23130388 | 0.79 | MAPT (0.54) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL20459373 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL3654988 | 0.78 | ACHE (0.54) | ALDH1A1LMNATAAR1KDM4EMAPT | |
| SCHEMBL29959275 | 0.78 | ACHE (0.54) | ALDH1A1LMNATAAR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |