Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977477 | 0.89 | DHODH (0.56) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14985323 | 0.86 | DHODH (0.55) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14985285 | 0.85 | DHODH (0.54) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14976930 | 0.80 | DHODH (0.64) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14977321 | 0.78 | DHODH (0.62) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL14977475 | 0.75 | DHODH (0.40) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14977653 | 0.74 | DHODH (0.60) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL14977772 | 0.73 | DHODH (0.60) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL14985241 | 0.72 | RAB9A (0.46) | KMT2AGAAMEN1 | |
| SCHEMBL14977409 | 0.71 | RAB9A (0.45) | KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |