Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985241 | 0.91 | RAB9A (0.46) | RAB9ANPC1KMT2AMEN1TNF | |
| SCHEMBL14985323 | 0.86 | DHODH (0.55) | RAB9ANPC1KMT2ATNFNR2F2 | |
| SCHEMBL14977429 | 0.80 | ATM (0.52) | RAB9ANPC1KMT2AMEN1GAA | |
| SCHEMBL14985285 | 0.79 | DHODH (0.54) | KMT2AGAA | |
| SCHEMBL14977653 | 0.75 | DHODH (0.60) | KMT2ANOD1GAA | |
| SCHEMBL14985324 | 0.71 | DHODH (0.61) | KMT2AMEN1NOD1GAA | |
| SCHEMBL14985302 | 0.71 | DHODH (0.52) | KMT2AMEN1GAA | |
| SCHEMBL14977651 | 0.71 | DHODH (0.47) | KMT2AMEN1NOD1 | |
| SCHEMBL14977772 | 0.68 | DHODH (0.60) | KMT2AMEN1GAA | |
| SCHEMBL31584155 | 0.66 | CA12 (0.60) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |